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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
17.58
Human Site:
S499
Identified Species:
32.22
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S499
P
G
R
S
I
S
G
S
I
P
A
G
R
T
V
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S499
P
G
R
S
I
S
G
S
I
P
A
G
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S499
P
G
R
S
V
S
G
S
V
P
A
G
R
T
I
Dog
Lupus familis
XP_534086
793
86791
P610
R
S
I
S
G
S
V
P
A
G
R
T
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
S499
P
G
R
S
I
S
G
S
I
P
A
G
R
T
V
Rat
Rattus norvegicus
XP_002725626
681
74519
S499
P
G
R
P
I
S
G
S
I
P
A
G
R
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
P457
R
P
A
G
G
L
G
P
G
R
P
S
S
G
P
Chicken
Gallus gallus
XP_421015
633
66869
G454
S
G
S
G
V
G
P
G
R
P
G
G
S
S
S
Frog
Xenopus laevis
Q6NU13
800
83727
N608
P
R
P
G
T
G
P
N
S
V
R
H
N
T
T
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
V461
P
K
R
M
E
R
G
V
S
G
S
Q
I
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
G420
Y
A
A
T
S
L
K
G
T
V
R
E
F
P
P
Honey Bee
Apis mellifera
XP_395689
579
67372
K418
P
K
M
K
I
L
D
K
Q
E
L
L
K
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
G439
D
S
R
A
D
P
P
G
K
S
S
R
P
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
80
13.3
N.A.
100
86.6
N.A.
6.6
20
13.3
20
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
86.6
N.A.
6.6
33.3
20
26.6
N.A.
6.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
0
0
8
0
39
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
47
0
24
16
16
54
24
8
16
8
47
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
39
0
0
0
31
0
0
0
8
0
8
% I
% Lys:
0
16
0
8
0
0
8
8
8
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
24
0
0
0
0
8
8
8
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
8
16
0
% N
% Pro:
62
8
8
8
0
8
24
16
0
47
8
0
8
8
16
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
16
8
54
0
0
8
0
0
8
8
24
8
39
0
8
% R
% Ser:
8
16
8
39
8
47
0
39
16
8
16
8
16
16
24
% S
% Thr:
0
0
0
8
8
0
0
0
8
0
0
8
0
47
8
% T
% Val:
0
0
0
0
16
0
8
8
8
16
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _